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#348: Omega-3 Supplementation & Heart Disease

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Listen on these AppsPodcast TranscriptsToday’s Topic in Focus: Omega-3 Supplementation & Heart Disease [01:52] 2018 Cochrane Review ASCEND Trial VITAL Trial REDUCE-IT GISSI-Prevenzione Hu et al., 2019 Meta-analysis “I Have a Question!” [66:30] Today’s listener question: “What do you guys think of the new obesity guidelines (UK government plan)?” Details: UK government press release Quack Asylum [87:00] Is a gram of PUFA in chicken worse than 250g of sugar from honey? Random Recommendations [94:20] Alan: Shelock – Netflix Series Danny: Profit & Cocaine – Planet MoneyPrevious EpisodesGo to all Previous EpisodesFan of the Podcast?If you regularly enjoy listening to Sigma …

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#347: Alex Thomas – Advancing the Sports Nutritionist Profession

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Listen on these AppsPodcast TranscriptsGuest InformationAlex Thomas Alex Thomas is the founder of Sports Nutrition Association (SNA), which is global association that contains Sports Nutrition Australia, Sports Nutrition NewZealand, Sports Nutrition Asia, and Sports Nutrition USA. Alex is an experienced Clinical Accredited Sports Nutritionist. He is the Australasian Ambassador of the ISSN (International Society of Sports Nutrition). He is co-creator of the Metabolic Health Screen (A health risk and contraindication identification and triage system – now imbedded in the MyPocketcoach platform). His passion is in providing legitimate education, qualifications and insurance pathways to ensure the successful and sustainable career pathways …

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#346: Kathryn Bradbury, PhD – Diet & Colorectal Cancer Risk

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Listen on these AppsPodcast TranscriptsGuest InformationKathryn Bradbury, PhD Dr. Kathryn Bradbury, PhD is a researcher at the University of Auckland, New Zealand. Her research has focused on examining the role of diet in the development of cancer, cardiovascular disease and other non-communicable diseases. Dr. Bradbury spent 5 years in the Cancer Epidemiology Unit at the University of Oxford. There, she worked as a nutritional epidemiologist on large cohort studies, including the European Investigation into Cancer and Nutrition (EPIC), and the UK Biobank. She also has expertise in traditional and web-based dietary assessment methods, nutritional epidmiology (including prospective analyses of large …

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#345: Rebecca Leech, PhD – Impact of Meal Patterning on Diet Quality & Health

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Listen on these AppsPodcast TranscriptsGuest InformationRebecca Leech, PhD Dr. Rebecca Leech is a Registered Nutritionist and Nutritional Epidemiologist, based at Deakin’s Institute for Physical Activity and Nutrition. Rebecca has a PhD in Nutritional Epidemiology, and in 2018, was awarded an Alfred Deakin Medal for her doctoral thesis, which examined adults’ eating patterns and their associations with diet quality and obesity. Her postdoctoral research, extends on this, and applies novel analytic approaches to understand determinants of food intake at eating occasions and the role of eating patterns in cardiometabolic health in adults. Dr. Leech is funded by an Alfred Deakin Postdoctoral …

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#344: Prof. Martin Caraher – Food Poverty & Food Aid Provision

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Listen on these AppsPodcast TranscriptsGuest InformationProfessor Martin Caraher, PhD Prof. Martin Caraher is Emeritus Professor of food and health policy at Centre for Food Policy at City, University of London. He has worked for and acted as a consultant to the UK Department of Health, the World Bank and the World Health Organisation. He was a member of the original London Food Board which developed the food strategy for London. He is a member of the International Obesity Task Force (IOTF) scientific committee. He also sits on the Safefood Irl scientific committee.In this episode we discuss: How food poverty extends …

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#343: Understanding Causality in Nutrition Science

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Get Sigma Synopsis EmailsToday’s Topic in Focus: Understanding Causality in Nutrition Science Inferring causality vs demonstrating causality Hierarchy of evidence vs. standards of proof The need for correlation, time precedence and non-spuriousness Reductionism and erroneous application of the biomedical model to nutrition The false causality dichotomy: RCTs vs. epidemiology Understanding what the “highest quality evidence available” is How nutritional epidemiology can infer causality Links: Deaton & Cartwright, 2018 – Understanding and misunderstanding randomized controlled trials Dawson-Hughes & Harris, 2002 – Calcium intake influences the association of protein intake with rates of bone loss in elderly men and women Blumberg et …

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#342: Are Vegan Diets Superior for Health?

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Get Sigma Synopsis EmailsIn this episode we discuss:Today’s Topic in Focus: Vegan Diets & Human Health Defining “plant-based” diets Examination of various intervention trials comparing diets Is veganism suitable across the lifestage? Benefits of a vegan diet Are there benefits to excluding animal products? Can the benefits of a vegan diet be gleaned whilst including animal foods? Nutrient considerations if deciding to eat vegan: a well-forumulated vegan diet Should athletes consider: creatine, carnosine, carnitine, leucine, etc.? Links: Research Referenced in this Episode: The BROAD study – Wright et al., 2017 Barnard et al., 2006 Barnard et al., 2009 “An Important …

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#340: Ethics of Veganism & Omnivorism (Part 4) – Diana Rodgers, RD & Robb Wolf

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Listen on these AppsPodcast TranscriptsGuest InformationDiana Rodgers and Robb Wolf are the co-authors of Sacred Cow, a book exploring the important role of animals in our food system.Diana Rodgers, RD Diana is a Registered Dietitian living on a working organic farm in New England, where she runs an active nutrition practice. She speaks at universities and conferences internationally about nutrition and sustainability, social justice, animal welfare and food policy issues. She’s just completed work on the new book and film project, Sacred CowRobb Wolf Robb Wolf is a former research biochemist and a New York Times/WSJ Best Selling author (for …

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#339: Prof. Corinna Hawkes – Food Policy, Food Systems & Public Health

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Listen on these AppsPodcast TranscriptsGuest InformationProf. Corinna Hawkes Professor Corinna Hawkes has been working for the past 20 years with UN agencies, governments, NGOs and academia at the local, national and international level to support the design of more effective policies throughout the food system to improve diets and prevent malnutrition in all its forms. She is currently Director of the Centre for Food Policy at City, University of London, UK, a Centre dedicated to shaping a more effective food system through education, research and engagement with the world of food policy. In 2018 she was appointed Vice Chair of …

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#338: Ethics of Veganism & Omnivorism (Part 3) – Alex O’ Connor

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Listen on these AppsPodcast TranscriptsGuest InformationAlex J. O’Connor Alex J. O’Connor is founder of the Cosmic Skeptic YouTube channel, podcast and blog; platforms dedicated to the publication of philosophical ideas and debates in an accessible format. He is currently reading for a degree in philosophy and theology at St John’s College, Oxford University. Alex is an impassioned animal rights advocate and religious critic, regularly discussing these topics on his online platforms. He has spoken at conferences internationally and has engaged in debates on ethics and philosophy.In this episode we discuss: How Alex evaluates the ethics of food choices Moral vs. …

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#337: Ethics of Veganism & Omnivorism (Part 2) – Prof. Paul Thompson

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Listen on these AppsPodcast TranscriptsGuest InformationProf. Paul Thompson, PhD Professor Paul B. Thompson holds the W.K. Kellogg Chair in Agricultural, Food and Community Ethics at Michigan State University, where he serves on the faculty in the departments of Philosophy, Community Sustainability and Agricultural, Food and Resource Economics. He received his Ph.D. in Philosophy from the State University of New York at Stony Brook and has held posts at Texas A&M University and Purdue University. Thompson’s research and teaching has focused on ethical and philosophical topics in food and agriculture. He is the author or co-author of over two hundred articles …

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#336: Ethics of Veganism & Omnivorism (Part 1) – Andrew Chignell, PhD

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Listen on these AppsPodcast TranscriptsGuest InformationProf. Andrew Chignell Andrew Chignell is a professor at Princeton, with appointments in Religion, Philosophy, and the University Center for Human Values. He was previously an associate professor at Cornell and a professor at University of Pennsylvania. He received his PhD from Yale. Chignell’s work to date focuses on Immanuel Kant and other modern European philosophers, philosophy of religion, the moral psychology of hope and despair, and the ethics of belief. He also has an interest in food ethics, and recently co-produced (with Will Starr at Cornell) a Massive Open Online Course on “The Ethics …

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#335: Kyra Bobinet, MD – Systems, Dietary Behaviour Change & the Iterative Mindset

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Listen on these AppsPodcast TranscriptsGuest InformationKyra Bobinet, MD, MPH Dr. Bobinet received her Masters in Public Health at Harvard University, specializing in Healthcare Management, Technology-enabled Behavior Change, and Population Health Management. She received her medical degree from the UCSF School of Medicine. She has also studied in Dr. BJ Fogg’s Persuasive Tech Lab at Stanford. Kyra has founded several healthcare start-ups, spanning behavior health, population health, and mobile health. She has designed behavior change programs, big data algorithms, billion dollar products, mobile health apps, and evidence-based studies in metabolic medicine.In this episode we discuss: The Iterative Mindset Behaviour change techniques …

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#334: Austin Baraki, MD – Potential Harms of Screening, Overdiagnosis and Overtreatment

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Listen on these AppsPodcast TranscriptsGuest InformationAustin Baraki, MD Dr. Austin Baraki is an Internal Medicine Physician, based in San Antonio, Texas. He completed his doctorate in medicine at Eastern Virginia Medical School, and Internal Medicine Residency at the University of Texas Health Science Center in San Antonio. He also works as a strength coach and puts out information via Barbell Medicine.In this episode we discuss: What do we want from a screening test? What criteria should it meet? Understanding test sensitivity, specificity and predictive value Harms of inappropriate screening or too much screening Overdiagnosis and overtreatment Lead time bias and …

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#333: Diet & Immunity

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Get Sigma Synopsis EmailsIn this episode we discuss:Today’s Topic in Focus: Immune Function & Diet Innate and adaptive immune response How does body composition impact immune function? Will a calorie deficit or fasting decrease immunity? Vitamins A, C, D. Supplementation with zinc: yes or no? Eating “to support the immune system” Exercise and immunity Environmental factors in infancy Links: Sigma Statement: Nutrition & Immune Function I Have a Question! Today’s Member Question: “The immune appears malleable in infancy. Growing up with pets appears to be beneficial. Exposure to peanuts decreases chance to developing peanut allergy. Are there other nutritional interventions …

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#332: Prof. Sam McConkey – COVID-19: Public Health Response, Clinical Presentation & Socioeconomics

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Listen on these AppsPodcast TranscriptsGuest InformationProf. Samuel McConkey,  Prof. Sam McConkey is a doctor and researcher specializing in the prevention and control of infectious diseases. Currently he is Associate Professor and Head of the Department of International Health and Tropical Medicine at the Royal College of Surgeons in Ireland. He is also a Consultant in General Medicine, Tropical Medicine and Infectious Diseases at Beaumont Hospital Dublin. Previously Prof. McConkey was a Research Fellow in Infectious Disease at Washington University School of Medicine in St. Louis, Missouri and an Honorary Consultant in Infectious Diseases at Oxford Radcliffe Trust.In this episode we …

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#331: Prof. Roy Taylor – Diabetes Remission, Very-low Calorie Diets & the Twin Cycle Hypothesis

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Listen on these AppsPodcast TranscriptsGuest InformationProf. Roy Taylor, MB ChB, MD Roy Taylor is Professor of Medicine and Metabolism at the University of Newcastle in the UK. There he is also director of the Newcastle Magnetic Resonance Centre. Prof. Taylor is an Honorary Consultant Physician at Newcastle Acute Hospitals NHS Trust. Since publishing his “twin cycle” hypothesis of type 2 diabetes in 2008, Prof. Taylor and colleagues have published several fascinating studies with potentially large implications for the potential to put diabetes into remission. Three of the most important trials were the Counterpoint Study, the Counterbalance study and the DiRECT …

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#330: Eric Trexler, PhD – Antioxidants, Oxidative Stress & Exercise Adaptations

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Listen on these AppsPodcast TranscriptsGuest InformationEric Trexler, PhD Eric Trexler is Director of Education at Stronger By Science, where he co-hosts the SBS podcast. He also is one of the four contributors to the MASS Research Review. Eric has a prolific background in exercise science research, with more than 30 publications to his name by the time he completed his PhD at UNC-Chapel Hill.In this episode we discuss: Antioxidants, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS). When our antioxidant systems are overwhelmed by the production of reactive species it leads to a state of oxidative stress …

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#329: Diet & Inflammation

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Get Sigma Synopsis EmailsIn this episode we discuss:Today’s Topic in Focus: Inflammation & Diet Defining inflammation Acute vs. chronic inflammation Local vs. systemic inflammation Does inflammation “cause” chronic disease? Does a poor diet cause chronic inflammation? Are some diets “anti-inflammatory”? Specific nutrients and claims of causing inflammation: PUFA, sugar, dairy, wheat, etc. Links: The Dietary Inflammatory Index (DII) Sydney Diet Heart Study Commentary on: Minnesota Coronary Experiment I Have a Question! Today’s Member Question: “Is the carcinogenic risk of this high enough that I should be throwing them away and starting again? International Agency for Research on Cancer (IARC) EFSA: …

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#328: Meeta Singh, MD – Sleep, Immunity & Mental Health

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Find the podcast on your app of choice hereGuest InformationMeeta Singh, MD Dr. Meeta Singh is a board-certified sleep medicine doctor and is currently the service chief of the sleep medicine at the Henry Ford sleep laboratory in Michigan. She did her training in psychiatry at the Mayo clinic and a sleep fellowship at the Henry Ford hospital. She is board-certified by the American Board of Psychiatry and Neurology as a psychiatrist and sleep medicine sub-specialist.In this episode we discuss: What sleep actually does that makes it so crucial Impact of sleep on immune function Impact of sleep on psychological …

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#327: David Dunne – Behavioural Science in Nutrition

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Find the podcast on your app of choice hereGuest InformationDavid Dunne David’s a Performance Nutritionist with a track record in developing and delivering nutrition programmes to elite athletes, teams, Olympians and sports legends – all over the globe. He has worked in elite sport with PGA Tour golfers and various teams including Harlequins (rugby union), Bradford Bulls (rugby league) and Queens Park Rangers (soccer). David is currently completing PhD out of Liverpool Johns Moores University in the UK, doing research on digital media & behaviour change interventions in sports nutrition. David is the CEO of Hexis.In this episode we discuss: …

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#326: Krista Scott-Dixon, PhD – Adaptability & Autonomy in the Nutrition Coaching Process

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Find the podcast on your app of choice hereGuest InformationKrista Scott-Dixon, PhD Dr. Krista Scott-Dixon is a former university professor and researcher who now designs curriculum for Precision Nutrition. She focuses on helping people make meaningful change through the Precision Nutrition Coaching and coaching Certification programs. Krista is also the author or co-author of several books, with the latest being Why Me Want Eat: Fixing Your Food Fuckedupitude.In this episode we discuss: Not mistaking the metrics for the goals The value of client autonomy in the coaching process Challenges for nutritionists and coaches in adapting to new situations Krista’s work …

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#325: Kirk Parsley, MD – Stress, Sleep & Anxiety During a Pandemic

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Find the podcast on your app of choice hereGuest InformationDr. Kirk Parsley Doc Parsley is a former SEAL, and received his Medical Degree from Bethesda, Uniformed Services University of Health Sciences (USUHS) in 2004. He served as an Undersea Medical Officer at Naval Special Warfare Group One from 2009 – 2013. While there, he led the development and supervised the group’s first Sports Medicine Rehabilitation center. Doc Parsley has been a member of the American Academy of Sleep Medicine since 2006 and has served as Naval Special Warfare’s expert on Sleep Medicine. After leaving the Navy he went into concierge …

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#324: Fatima Cody Stanford, MD – Obesity Treatment & Weight Bias

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Find the podcast on your app of choice hereGuest InformationFatima Cody Stanford, MD, MPH, MPA Dr. Fatima Cody Stanford is an obesity medicine physician, scientist, educator, and policy maker at Massachusetts General Hospital and Harvard Medical School. She is a national and international sought after expert in obesity medicine who bridges the intersection of medicine, public health, policy, and disparities. She completed her Obesity Medicine & Nutrition Fellowship at MGH/HMS after completing her internal medicine and pediatrics residency at the University of South Carolina. She has served as a health communications fellow at the Centers for Disease Control and Prevention …

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#323: COVID-19 & SARS-CoV-2 with Rizwan Sohail, MD

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Find the podcast on your app of choice Guest BioM. Rizwan Sohail, MD Dr. Rizwan Sohail is an infectious disease specialist based at the Mayo Clinic, where he holds a joint appointment with the divisions of Infectious Diseases and Cardiovascular Diseases. He completed his internship and residency in internal medicine at Michael Reese Hospital in Chicago and then a Fellowship in infectious diseases at the Mayo Clinic. In This Episode We Discuss Distinguishing between COVID-19 (disease) and the actual novel coronavirus (SARS-CoV2) What is different about this specific coronavirus compared to others This coronavirus has a respiratory droplet transmission The difference …

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#321: Dave Feldman & Alan Flanagan – Debating LDL Causality & the “Lipid Triad”

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Find the podcast on your app of choice Guest BioDave Feldman Dave Feldman is a software engineer and runs the Cholesterol Code website. In 2015 Dave adopted a low-carb high-fat diet, which improved his overall health. However, upon seeing his LDL-cholesterol skyrocket, he set out learn all he could about blood lipids and health. Dave has gained prominence as a “LDL-skeptic” and promoter of his “lipid triad” hypothesis. This lipid triad relates to a situation where one sees high LDL-C, high HDL-C and low triglycerides. Dave hypothesises that in such a context, the high LDL-C does not confer high risk of …

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#317: Understanding Diet & Heart Disease Risk

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Find the podcast on your app of choice In This Episode We DiscussThis episode is a supplemental/follow-up episode to the ‘Diet & Cardiovascular Disease’ Series of Sigma Statements. If you have not read those statements, you can find them here: Cholesterol, Lipoproteins & Lipids: Understanding CVD Risk The Impact of Diet on Blood Lipids How Diet Influences Heart Disease Risk In this podcast Danny and Alan will be re-capping the main important points from each statement, in addition to addressing follow-up questions or potential conflicting points. We’ll cover issues such as: Does ApoB testing make LDL-C irrelevant? “I heard PUFA/omega-6 increases …

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#313: Fergus Connolly, PhD – Authenticity, Elite Human Performance & Getting the Best From Others

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Find the podcast on your app of choice Guest BioFergus Connolly, PhD Dr. Fergus Connolly is one of the world’s foremost human performance thought leaders and influencers, and has applied performance science with leading sports, military, and business teams. He is the only coach to have full times roles in every major sport. Fergus has served as Director of Elite Performance for the San Francisco 49ers, Sports Science Director with the Welsh Rugby Union, and Performance Director for University of Michigan Football. He has guided coaches, support staff and players in the NBA, Australian Rules Football and international cricket. Fergus has …

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#300: The Random Episode

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Find the podcast on your app of choice Sigma Nutrition Radio has reached the 300th episode! To mark the occassion, Patreon supporters of the podcast and subscribers to the Sigma Synopsis email were able to submit questions about anything they wished. In this episode, Gar Benn joins me to go through some of the questions submitted. This episode focuses on all the random questions submitted about a range of things, from my schedule to religion to career highlights to living in Ireland, and everything in between! Any nutrition-related questions will be covered in a separate episode.Questions Answered: Which one of your …

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#294: Nicola Guess, PhD, RD – Prediabetes & Type 2 Diabetes Nutrition

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Guest BioNicola Guess, PhD, RD Nicola Guess is a Registered Dietitian with a PhD in the dietary management of prediabetes from Imperial College London. She is currently Head of the Nutrition Unit at Dasman Diabetes Institute (DDI) in Kuwait. Nicola is a research fellow at King’s College London where her research focuses on the role of diet in the prevention and management of type 2 diabetes. She has a particular interest in the use of low-carbohydrate diets in the management of type 2 diabetes, and leads a research programme investigating dietary modification – including increasing protein or the use of …

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SNR #265: Lessons From Experts – Prediabetes, Autophagy, Relative Energy Deficiency and Carbohydrate Periodization

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About This EpisodeThe Sigma Live Sessions include four topic discussions on: 1) Dietary Interventions in Prediabetes & Diabetes – Nicola Guess, PhD 2) Fuelling Elite Sport Performance, Carbohydrate Periodization & Pracitioner Experiences – James Morton, PhD 3) Relative Energy Deficiency & Female Athlete Triad – Kirsty Elliot-Sale, PhD 4) Fasting for Health? Longevity, Autophagy and More – Martin MacDonald, MSc Full interviews: Kirsty Elliot-Sale, PhD – Energy Availability, Menstrual Disorders & RED-S James Morton, PhD – Fuelling Elite Sport: Team Sky, Liverpool FC & Carbohydrate Periodization Nicola Guess, PhD, RD – Prediabetes & Type 2 Diabetes Nutrition About This EpisodeThe …