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Read our recent Sigma Statements
One propsed intervention that has garnered a lot of excitement, owing to some interesting research, is the potential use of fasting to increase longevity and/or healthspan. Within this broad category, various different dietary interventions have been suggested, including various forms of intermittent fasting, time-restricted eating, dietary restriction of certain nutritients, calorie restriction or a “fasting-mimicking” diet.
But what does the current evidence tell us? Do the conclusions match the excitement? Which claims are grounded in solid science and which ones are pseudoscientific extrapolations?
Vitamin D deficiency has been proposed to play a role in coronavirus infection. In addition, vitamin D supplementation has been explored as a potential adjunct treatment for those with severe COVID-19 infection. This Sigma Statement aims to summarize the available evidence regarding the potential role of vitamin D status, vitamin D genotypes and vitamin D supplementation and the risk of COVID-19 infection and mortality.
Can the bacteria in our gut impact our mood? This Sigma Statement examines the evidence on this interaction, including a discussion of what we know about the gut-brain axis.
There are sometimes claims about low LDL-C being associated with increased mortality and detrimental health outcomes. But is this “cholesterol paradox” an accurate interpretation of the evidence? In this Sigma Statement we explore this claim and bring some clarity to the conversation.
This Statement will discuss current evidence for nutrient deficiencies in the developed world. Particular attention will be placed on iron, vitamin D, zinc, folate (vitamin B9), and iodine.
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