#383: Irritable Bowel Syndrome (IBS) & Diet

Today's Topic in Focus: IBS & Diet [06:20]

In this episode Danny and Alan discuss irritable bowel syndome and the evidence related to dietary interventions. They discuss diagnosis of the condition, various sub-types, potential mechanisms, the gut-brain axis, first line treatments, impact of fibre, and evidence on the low FODMAP diet.

Studies referenced in this episode:

1. Marshall et al., 2010 - Eight year prognosis of postinfectious irritable bowel syndrome following waterborne bacterial dysentery
2. Drossman et al., 2009 - International survey of patients with IBS: symptom features and their severity, health status, treatments, and risk taking to achieve clinical benefit
3. Holtmann et al., 2016 - Pathophysiology of irritable bowel syndrome
4. Böhn et al., 2015 - Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome as Well as Traditional Dietary Advice: A Randomized Controlled Trial
5. Altobelli et al., 2017 - Low-FODMAP Diet Improves Irritable Bowel Syndrome Symptoms: A Meta-Analysis
6. Maagaard et al., 2016 - Follow-up of patients with functional bowel symptoms treated with a low FODMAP diet
7. Biesiekierski et al., 2013 - No Effects of Gluten in Patients With Self-Reported Non-Celiac Gluten Sensitivity After Dietary Reduction of Fermentable, Poorly Absorbed, Short-Chain Carbohydrates
8. Tarpila et al., 2004 - Efficacy of ground flaxseed on constipation in patients with irritable bowel syndrome
9. Bijkerk et al., 2009 - Soluble or insoluble fibre in irritable bowel syndrome in primary care? Randomised placebo controlled trial
10. Halmos et al., 2014 - A diet low in FODMAPs reduces symptoms of irritable bowel syndrome

"I Have a Question!"  [74:47]

Today's questions:

1. "What do we know about co-morbidities associated with IBS and how to manage these (e.g. brain fog, acne, etc.)?"
2. How to control IBS on a vegan diet?

Quack Asylum [79:30]

Dr. David Perlmutter's claims about diet's role in dementia and other brain-related issues.

Related content:

• The Problem With David Perlmutter, the Grain Brain Doctor - By Alan Levinovitz
• Red Pen Reviews review of Grain Brain

Random Recommendations [86:49]

Alan's Recommendation: The Great (2020 TV series)

Danny's Recommendation: American Prodigy podcast series - Freddy Adu: The Legend of Freddy (Links: Apple Podcasts, Google Podcasts, Spotify)