#352: Do Diets Even Work in the Long-term? – A Look at Weight Loss Maintenance

Today's Topic in Focus: Weight Regain vs Weight Loss Maintenance [02:56]

• Pownall et al., 2015 - Changes in Body Composition over Eight Years in a Randomized Trial of a Lifestyle Intervention: The Look AHEAD Study

• Purcell et al., 2014 - The effect of rate of weight loss on long-term weight management: a randomised controlled trial

• Thomas et al., 2014 - Weight-loss maintenance for 10 years in the National Weight Control Registry

"I Have a Question!" [58:56]

Today's listener question: "How does the ApoE4 allele affect lipid metabolism? And how should someone structure their diet around having one or both alleles due to it resulting in higher LDL-C than someone without the gene?"

Quack Asylum [63:09]

Nutrition recommendations without any evidence, given by Dr. Mary Ryan between 19 and 22 minutes of this podcast episode.

Non-evidence-based claims made in that discussion [with time-stamps]:

1. [19.30] In reference to drinking water in the morning: "As women, we've a slower metabolism... so we need to get it going"
2. [20.01] "Sugar is toxic"
3. [21.20] "You can only have two slices of bread and that's it."
4. [21.27] "It's all about getting circadian rhythm in the bowel, so you have to eat little and often to keep the metabolism going."
5. [21.42] Eating little and often is important "particularly in women, as we've a slow metabolism, and we need to trigger it".
6. [21.50] Only eat carrots, parsnips and turnips (the root vegetables) at the weekend, as they store sugar. Just have green veg at dinner during the week.

Random Recommendations [76:35]

Alan's Recommendation(s):

1. Cynical Theories : How Activist Scholarship Made Everything about Race, Gender, and Identity--And Why This Harms Everybody - Plcukrose & Lindsay
2. Helen Pluckrose: The Evolution of Postmodern Thought

Danny's Recommendation:

• Sheldon Solomon: Death and Meaning | Lex Fridman Podcast #117
• Humanity at the Crossroads | Sheldon Solomon | TEDxSkidmoreCollege