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SNR #81: Joseph Agu – Protein Synthesis, Amino Acids & Pre-bed Casein

In Podcasts by Danny Lennon1 Comment

Episode 81: Nutritionist and doctoral researcher Joseph Agu is on the show to discuss pre-bed casein, protein quality, absorption rates of different whey supplements and the usefulness of branched-chain amino acids.



Guest Bio

Joseph  Agu 


Joseph is a Performance Nutritionist, formerly at the English Institute of Sport (EIS) working with British Athletics, and now solely at his own consultancy.

He completed a BSc. in Sport and Exercise Science as well as a MSc. in Sports Nutrition. And is now currently undertaking a PhD at Bangor University where he’s looking at nutritional interventions for strength and power athletes.

 In this episode we discuss:

  • Nitrogen balance, muscle protein synthesis (MPS) and muscle protein breakdown (MPB)
  • Difference between muscle protein synthesis and whole body protein synthesis
  • Is pre-bed casein superior to a strategy that does not include such timing?
  • Difference in MPS rates between different protein sources
  • Just how useful is branched-chain amino acid (BCAA) supplementation for body composition goals?

Links & Resources:

BCAAs for Bodybuilders (Part 1 of 4)

Alan Aragon’s Research Review

The effect of protein timing on muscle strength and hypertrophy: a meta-analysis – Schoenfeld, Aragon & Krieger

English Institute of Sport

Groen et al., 2012 – Intragastric protein administration stimulates overnight muscle protein synthesis in elderly men

Res et al., 2012- Protein ingestion before sleep improves post-exercise overnight recovery

Snijders et al., 2015 – Protein Ingestion before Sleep Increases Muscle Mass and Strength Gains during Prolonged Resistance-Type Exercise Training in Healthy Young Men

Burk et al., 2009 – Time-divided ingestion pattern of casein-based protein supplement stimulates an increase in fat-free body mass during resistance training in young untrained men

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