#330: Eric Trexler, PhD – Antioxidants, Oxidative Stress & Exercise Adaptations

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Eric Trexler, PhD

Eric Trexler is Director of Education at Stronger By Science, where he co-hosts the SBS podcast. He also is one of the four contributors to the MASS Research Review.

Eric has a prolific background in exercise science research, with more than 30 publications to his name by the time he completed his PhD at UNC-Chapel Hill.

In this episode we discuss:

  • Antioxidants, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS).
  • When our antioxidant systems are overwhelmed by the production of reactive species it leads to a state of oxidative stress
  • Bi-directional relationship between oxidative stress and inflammation
  • Antioxidants are just "one thing"
  • A certain amount of reactive species is needed for physiological function.
  • Is the impact of antioxidant supplementation dependent on the free radical burden at the time of supplementation?
  • How much of an improvement in endogenous antioxidant status does exercise confer?
  • Antioxidants in food vs. in supplements
  • Tthe inflammatory response is part of driving training adaptations. The logic has thus been to avoid acute high-dose antioxidants in the immediate recovery window. Is this an evidence-based position?

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