Guest Information
Brendon Stubbs, PhD
Dr. Brendon Stubbs, PhD, is a Senior Clinical Lecturer and researcher at King's College London, conducting research in physical activity & mental health, the mind-body interface, and meta-research. He has published over 650 academic papers in several leading journals across multiple scientific fields.
Dr. Stubbs is also a clinical physiotherapist, being Head of Physiotherapy at the South London and Maudsley NHS Foundation Trust. He has a MSc in Neurological Rehabilitation & PhD in Pain Medicine & Rehabilitation. He has also informed policy guidelines in the UK, Europe and the World Health Organization.
In this episode we discuss:
- Movement levels as a risk factor, most notably depression
- A meta-analysis of prospective cohort studies in 2018, looking at physical activity and incident depression.
- This link between movement and depression has been looked at in some Mendelian Randomization studies
- Those who had a genetic pre-disposition to depression, but were most active had lower risk, than those who were less active
- Meta-analyses: the good and the bad
- What is "success" in terms of an intervention and depression
- Heterogeneity of exposure (activity type) and outcome (symptoms, diagnosis, etc.)
- Multifacted and complex nature of depression
Links & Resources
- Click here to join the email list to receive our weekly Sigma Synopsis emails
- Schuch et al., 2018 - Physical Activity and Incident Depression: A Meta-Analysis of Prospective Cohort Studies
- Schuch et al., 2016 - Are lower levels of cardiorespiratory fitness associated with incident depression? A systematic review of prospective cohort studies
- Choi et al., 2019 - Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study
- Schuch & Stubbs, 2019 - The Role of Exercise in Preventing and Treating Depression
- Kandola et al., 2019 - Physical activity and depression: Towards understanding the antidepressant mechanisms of physical activity
- Instagram: @brendon.stubbs
