Episode 184: We take a deeper look at artificial/non-caloric sweeteners; effects on bodyweight, glucose tolerance, gut flora and health. What does the evidence say about safety and health concerns?
Listen on Stitcher (Android app)
Links/References:
- Magnuson et al., 2017 – Critical review of the current literature on the safety of sucralose
- Bian et al., 2017 – The artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice
- Uebanso et al., 2017 – Effects of Low-Dose Non-Caloric Sweetener Consumption on Gut Microbiota in Mice
- Suez et al., 2014 – Artificial sweeteners induce glucose intolerance by altering the gut microbiota
- Johnston & Foreyt, 2014 – Robust scientific evidence demonstrates benefits of artificial sweeteners
- Temizkan et al., 2015 – Sucralose enhances GLP-1 release and lowers blood glucose in the presence of carbohydrate in healthy subjects but not in patients with type 2 diabetes
- Anton et al., 2010 – Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels
- Sharma et al., 2016 – Artificial sweeteners as a sugar substitute: Are they really safe?
- Schiffman et al., 1987 – Aspartame and Susceptibility to Headache
- Mallikarjun & Sieburth, 2015 – Aspartame and Risk of Cancer: A Meta-analytic Review
- Magnuson et al., 2016 – Biological fate of low-calorie sweeteners
- Pepino, 2015 – Metabolic Effects of Non-Nutritive Sweeteners
- Fowler, 2016 – Low-calorie sweetener use and energy balance: Results from experimental studies in animals, and large-scale prospective studies in humans
- EFSA Panel, 2011 – Scientific Opinion on the substantiation of health claims related to the sugar replacers xylitol, sorbitol, mannitol, maltitol, lactitol, isomalt, erythritol, D-tagatose, isomaltulose, sucralose and polydextrose and maintenance of tooth mineralisation by decreasing tooth demineralisation
- EFSA Panel, 2013 – Scientific Opinion on the re-evaluation of aspartame (E 951) as a food additive
- Fitch & Keim, 2012 – Position of the Academy of Nutrition and Dietetics: Use of Nutritive and Nonnutritive Sweeteners
- Tate et al., 2012 – Replacing caloric beverages with water or diet beverages for weight loss in adults
- Maersk et al., 2012 – Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot
- Renwick & Molinary, 2010 – Sweet-taste receptors, low-energy sweeteners, glucose absorption and insulin release
- Ma et al., 2009 – Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects
- Moller 1991 – Effect of Aspartame and Protein, Administered in Phenylalanine-Equivalent Doses, on Plasma Neutral Amino Acids, Aspartate, Insulin and Glucose in Man
- Wolf-Novak et al., 1990 – Aspartame ingestion with and without carbohydrate in phenylketonuric and normal subjects: effect on plasma concentrations of amino acids, glucose, and insulin
- Horwitz et al., 1988 – Response to single dose of aspartame or saccharin by NIDDM patients
Thought this was good? Click here to share on Facebook