#299: Mark Hopkins, PhD – Compensatory Eating, Exercise-induced Weight Loss & Energy Balance Homeostasis

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Mark Hopkins, PhD

Dr. Mark Hopkins is a lecturer in nutritional physiology at the University of Leeds, UK. His research focuses primarily on the physiological mechanisms of appetite control, and the interaction between diet, physical activity and appetite control. This includes examining the physiological and behavioural responses to dietary and exercise-induced weight loss.

Mark is a member of the Association for the Study of Obesity, the British Association of Sport & Exercise Science and The Nutrition Society.

• Adaptive thermogenesis – interplay between EI and EE
• Compensation to energy imbalance appears asymmetrical
• Metabolic adaptations that occur with hypocaloric dieting vs. deficit induced via increased exercise
• Post-exercise compensatory eating
• People have different weight loss responses to exercise interventions, not explained by adherence
• Does change in LBM influence hunger/appetite?
• Sedentary behaviour (physical inactivity): regulated zone vs. unregulated zone

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• Hopkins et al., 2019 – Activity energy expenditure is an independent predictor of energy intake in humans
• Hopkins & Blundell, 2016 – Energy balance, body composition, sedentariness and appetite regulation: pathways to obesity
• Casanova et al., 2019 – Biopsychology of human appetite — understanding the excitatory and inhibitory mechanisms of homeostatic control
• Hopkins et al., 2016 – Differing effects of high-fat or high-carbohydrate meals on food hedonics in overweight and obese individuals

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