#302: Leonie Heilbronn, PhD – Alternate-Day Fasting, Early Time-Restricted Feeding & Caloric Restriction

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Leonie Heilbronn, PhD

Associate Professor Leonie Heilbronn is the leader of the Obesity and Metabolism group based at the University of Adelaide, Australia.

She has a sustained record of translating basic discoveries in nutrition to humans and has contributed to current concepts of caloric restriction (CR), intermittent fasting (IF) and time restricted eating (TRE) in humans.

She is keenly interested in understanding mechanisms of insulin resistance in skeletal muscle and in adipose tissue utilising nutritional perturbations. She is an Associate Editor of Obesity and Obesity Research and Clinical Practice.

• Why are caloric restriction & fasting examined in relation to longevity?
• Alternate-day fasting (ADF)
• Is there reason to worry about greater LBM losses with ADF?
• Length of fasting window?
• Extent of caloric restriction during the fast?
• How important is calorie distribution across the day?
• TRFe vs TRFd paper (Hutchinson et al., 2019)
• Is benefit of eTRF down to timing of meals or duration of fast?

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• Hutchinson et al., 2019 – Time-Restricted Feeding Improves Glucose Tolerance in Men at Risk for Type 2 Diabetes: A Randomized Crossover Trial
• Hutchinson & Heilbronn, 2016 – Metabolic impacts of altering meal frequency and timing – Does when we eat matter?
• Heilbronn & Panda, 2019 – Alternate-Day Fasting Gets a Safe Bill of Health
• Leonie’s publications available on PubMed

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