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Introduction
This is the second episode in a new series called “Nutrition Science Explained”, in which members of the Sigma team will take a concept commonly mentioned in discussions about nutrition science, and explain what it is, give more background context, and highlight important aspects to know. The goal is to aid listeners to have a deeper understanding of other episodes when such concepts are mentioned.
In this episode Alan Flanagan discusses the concept of the GRADE system, and specifially how it applies to evaluating nutrition research and coming to conclusions for practice.
GRADE (Grading of Recommendations, Assessment, Development and Evaluations) is a framework for developing and presenting summaries of evidence and provides a systematic approach for grading the quality of evidence and making clinical practice recommendations.
Related resources
- What is GRADE? – BMJ Overview
- Tobias et al., 2021 – Grading nutrition evidence: where to go from here?
- Schwingshackl et al., 2016 – NutriGrade
- NutriRECs papers are discussed in this Sigma Statement: Is Red Meat Good or Bad for Health?
- [02:02]Understanding chronotypes
- [06:26]Measuring chronotypes
- [15:12]Genetic and environmental influences on chronotypes
- [28:34]Health implications of chronotypes
- [52:21]Practical applications
The Hosts
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Dr. Alan Flanagan has a PhD in nutrition from the University of Surrey, where his doctoral research focused on circadian rhythms, feeding, and chrononutrition.
This work was based on human intervention trials. He also has a Masters in Nutritional Medicine from the same institution.
Dr. Flanagan is a regular co-host of Sigma Nutrition Radio. He also produces written content for Sigma Nutrition, as part of his role as Research Communication Officer.
Danny Lennon has a master’s degree (MSc.) in Nutritional Sciences from University College Cork, and he is the founder of Sigma Nutrition.
Danny is currently a member of the Advisory Board of the Sports Nutrition Association, the global regulatory body responsible for the standardisation of best practice in the sports nutrition profession.