SNR #271: Prof. John Hawley – Circadian Metabolomics & Time-Restricted Feeding

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SNR #271: Prof. John Hawley – Circadian Metabolomics & Time-Restricted Feeding

Guest Bio

John Hawley, PhD

Prof. Hawley is Director of the Mary MacKillop Institute for Health at Australian Catholic Universtiy in Melbourne, Australia.

He has published over 220 scientific manuscripts, written over 100 articles for technical journals and has authored numerous book chapters for exercise biochemistry and sports medicine texts.

He is an Associate Editor for Diabetologia and currently sits on the Editorial Boards of many international journals. He is a frequently invited speaker at both National and International scientific meetings.

John’s primary research focus includes the interaction of exercise and diet on the regulation of fat and carbohydrate metabolism, particularly within skeletal muscle, the molecular basis of exercise training adaptation and the cellular bases underlying exercise-induced improvements in insulin action.

In This Episode We Discuss

  • Current work being done by Prof. Hawley’s lab on circadian metabolomics
  • Defining the human metabolome and circadian metabolomics
  • Comparative analysis of the circadian metabolome in the serum versus peripheral tissues (i.e., skeletal muscle)
  • Impact of high-fat or high-carb diet on the daily variation in metabolites
  • How dietary intake is a strong zeitgeber for peripheral clocks
  • Tissue-specificity of the human circadian metabolome
  • Time-restricted feeding in animal models and in humans
  • Prof. Hawley’s paper published (with Louise Burke) in Science in November: “Swifter, higher, stronger: What’s on the menu?”

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